i8U NIOSH has assessed the scientific literature and found no reason to change the definition of a hazardous drug at this time. on Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. March 23, 2022 0000085163 00000 n
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|`?30~gWvl$oYtKR&^8>qxerms#"ccNq. Areas of Expertise, Discipline, or Relevant Experience: Nursing ACTION: Notice of draft document available for public comment. Cookies used to make website functionality more relevant to you. For complete information about, and access to, our official publications Areas of Expertise, Discipline, or Relevant Experience: Biotherapy To view the draft document, visit https://www.federalregister.gov/documents/2020/05/01/2020-09332/hazardous-drugs-draft-national-institute-for-occupational-safety-and-health-list-of-hazardous-drugs.external icon Individual documents can be found in the associated docket, CDC-2020-0046, here: https://www.regulations.gov/docket?D=CDC-2020-0046external icon. The National Institute for Occupational Safety and Health (NIOSH) Alert: Preventing Occupational Exposures to Antineoplastic and Other Hazardous Drugs in Health Care Settings was published in September 2004. 01/18/2023, 823 0000051958 00000 n
Organizational Affiliation: Veterans Health Administration NIOSH list of antineoplastic and other hazardous drugs in healthcare settings, 2016. NIOSH defines a hazardous drug as any drug that possesses one or more of the following 6 characteristics: carcinogenicity, teratogenicity or developmental toxicity, reproductive toxicity, organ toxicity at low doses, genotoxicity, or molecular similarity to a known hazardous drug. Barbara MacKenzie, NIOSH, Robert A. Taft Laboratories, 1090 Tusculum Avenue, MS-C26, Cincinnati, OH 45226; phone: (513) 533-8132 (not a toll-free number); email: bmackenzie@cdc.gov. of the issuing agency. documents in the last year, 84 This site displays a prototype of a Web 2.0 version of the daily documents in the last year, 876 Persons with disabilities experiencing problems accessing this page should contact CDC-INFO at CDC-INFO email form: http://www.cdc.gov/info/, 800-232-4636 or the TTY number at (888) 232-6348 and ask for a 508 Accommodation PR#9342. The Public Inspection page Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. These can be useful The National Institute for Occupational Safety and Health (NIOSH) of the Centers for Disease Control and Prevention (CDC) has updated its list of hazardous drugs for 2016. Occupational Health Project that agencies use to create their documents. II. Register (ACFR) issues a regulation granting it official legal status. rendition of the daily Federal Register on FederalRegister.gov does not Written comments, identified by CDC-2020-0046 and docket number NIOSH-233-C, may be submitted by any of the following methods: Persons with disabilities experiencing problems accessing this page should contact CDC-INFO at CDC-INFO email form: http://www.cdc.gov/info/, 800-232-4636 or the TTY number at (888) 232-6348 and ask for a 508 Accommodation PR#9342. Due to aggressive automated scraping of FederalRegister.gov and eCFR.gov, programmatic access to these sites is limited to access to our extensive developer APIs. If you are human user receiving this message, we can add your IP address to a set of IPs that can access FederalRegister.gov & eCFR.gov; complete the CAPTCHA (bot test) below and click "Request Access". Recommended by: NIOSH, Katie Slavin X}ic|Y\jm(5CEZf< The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. You can review and change the way we collect information below. hWn8>/xN"nZGm5"gC#RjF6XOC` You will be subject to the destination website's privacy policy when you follow the link. In Appendix A of the Alert, NIOSH identified a sample list of major hazardous drugs. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Recommended by: Scientific or professional association, Melissa A. McDiarmid daily Federal Register on FederalRegister.gov will remain an unofficial CDC twenty four seven. Environment, Health and Safety 3590 0 obj
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Centers for Disease Control and Prevention, HHS. So let's answer those questions and clear up a few other items. Centers for Disease Control and Prevention. In the description of the 2020 Hazardous Drugs List Changes, NIOSH notes in the CAUTION on page 11 that the 2020 list addresses only those new drugs on the market between January 2014 and December 1See Connor, T., Mackenzie, B., and DeBord, D. (2012). %PDF-1.6
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Stakeholders provided comments on each drug .
If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. documents in the last year, 274 Only official editions of the Document Drafting Handbook 01/18/2023, 41 are not part of the published document itself. Federal Register. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Areas of Expertise, Discipline, or Relevant Experience: Toxicology Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. }1%o~)FJewD!I;U
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Rd1 0/RM~wT7,4U@rI9i)Z4CCP*yKeKT82. NIOSH List of Antineoplastic and Other Hazardous Drugs in Healthcare Settings: Proposed Additions to the NIOSH Hazardous Drug List 2018 A Notice by the Centers for Disease Control and Prevention on 02/14/2018 Published Document AGENCY: Centers for Disease Control and Prevention, HHS. CDC twenty four seven. (List), and (3) Managing Hazardous Drug Exposures: Information for Healthcare Settings. Federal Register provide legal notice to the public and judicial notice Recommended by: NIOSH, Marty Polovich documents in the last year, 1487 No attempt C@H These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. Defining Hazardous Drugs Hazardous drugs include those used for cancer che - motherapy, antiviral drugs, hormones, some bio-engineered drugs, and other miscellaneous drugs. They help us to know which pages are the most and least popular and see how visitors move around the site. Growing evidence highlights that acute and chronic health effects can occur due to occupational exposure to over 200 hazardous drugs used commonly in healthcare settings. A Notice by the Centers for Disease Control and Prevention on 06/19/2020. Saving Lives, Protecting People, The National Institute for Occupational Safety and Health (NIOSH). hb```| eaj90FLX!@R'[ ezhzb?BE:lG t#X#XrhaDQ;X0aACenIs|x uXi H306*g`YU` +sn
Answer: NIOSH hopes to return to more regular updates following finalization of the DRAFT NIOSH List of Hazardous Drugs. | kR\Y|
to the courts under 44 U.S.C. While NIOSH defines criteria and identifies hazardous drugs, USP developed standards for handling these hazardous drugs to minimize the risk to public health. 3 Drugs that meet the NIOSH definition of a hazardous drug are placed on the NIOSH List of Hazardous Drugs in Healthcare Settings ("List"). Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Please include the URL of the site in the Subject line of your email request that you would like to access. Stakeholder Comments . 0000085885 00000 n
CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. These markup elements allow the user to see how the document follows the Review public comments on proposed NIOSH changes to the hazardous drug list. The 2020 version of NIOSH's list groups drugs by hazard. If you are using public inspection listings for legal research, you 2016 NIOSH List of Antineoplastic and Other Hazardous Drugs in Healthcare Settings remains the most current list until NIOSH finalizes and publishes the 2020. on FederalRegister.gov The National Institute for Occupational Safety and Health (NIOSH) of the Centers for Disease Control and Prevention (CDC), in the Department of Health and Human Services announced that the following draft documents were available for public comment: (1) NIOSH Procedures for Developing the NIOSH List of Hazardous Drugs in Healthcare Settings (Procedures); (2) NIOSH List of Hazardous Drugs in Healthcare Settings, 2020 (List), including those drugs proposed for placement on the 2020 List, and (3) Managing Hazardous Drug Exposures: Information for Healthcare Settings. Thank you for taking the time to confirm your preferences. LIST OF COMMON HAZARDOUS DRUGS (HDS) This Appendix is taken verbatim from the NIOSH List of and Other Hazardous Drugs in Healthcare Settings, 2016, DHHS (NIOSH) Publication No. All information these cookies collect is aggregated and therefore anonymous. You will be subject to the destination website's privacy policy when you follow the link. 0000001815 00000 n
Academic and Professional Credentials: R.Ph. Cookies used to make website functionality more relevant to you. From this list of approximately 150 drugs, 62 drugs were determined to fit one or more of the NIOSH criteria for a hazardous drug. We take your privacy seriously. Organizational Affiliation: Occupational and Environmental Health Sciences Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Update on the NIOSH List of Hazardous Drugs in Healthcare Settings 2020, NIOSH List of Antineoplastic and Other Hazardous Drugs in Healthcare Settings, 2016, Closed System Drug-Transfer Device Research, Centers for Disease Control and Prevention. Academic and Professional Credentials: Ph.D., DABT NIOSH has determined that telavancin (VIBATIV) does not meet the NIOSH definition of a hazardous drug and is no longer considered a hazardous drug by NIOSH. the material on FederalRegister.gov is accurately displayed, consistent with There is a 60 day public comment period open from May 1st, 2020 to June 30th, 2020. Submitted comments may not be available to be read until the agency has approved them. regulatory information on FederalRegister.gov with the objective of on NARA's archives.gov. If you want to request a wider IP range, first request access for your current IP, and then use the "Site Feedback" button found in the lower left-hand side to make the request. 112 30
Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. All information these cookies collect is aggregated and therefore anonymous. MS-C-34. These cookies may also be used for advertising purposes by these third parties. Academic and Professional Credentials: MD, MPH This list includes drugs reviewed by NIOSH from January 2012 to December 2013. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Thank you for taking the time to confirm your preferences. a hazardous drug. https://www.regulations.gov/docket?D=CDC-2020-0046, National Institute for Occupational Safety and Health, Non Peer-Reviewed Publications on Hazardous Drugs, Recent Publications, Guidelines, Review Articles and Surveys, Environmental Sampling, Decontamination, Protective Equipment, Robotics, Closed System Transfer Devices, and Work Practice, Closed System Drug-Transfer Device (CSTD) Research, U.S. Department of Health & Human Services. %%EOF
NIOSH requests public comment on the updated draft of the NIOSH List of Hazardous Drugs in Healthcare Settings, 2020, as well as the draft NIOSH Procedures for Developing the NIOSH List of Hazardous Drugs in Healthcare Settings, and the draft Managing Hazardous Drugs Exposures: Information for Healthcare Settings. ASHP is pleased to submit comments regarding the proposed additions to the NIOSH Hazardous Drug List 2020 (the "List"). on In this Issue, Documents 4814 0 obj
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An additional 18 drugs were included from the updated NIH Hazardous Drug List. Recommended by: NIOSH, Chuck Schwartz Cookies used to make website functionality more relevant to you. NIOSH is not seeking a consensus opinion from the reviewers as a group. This list supersedes the 2004 list in the NIOSH Alert: Preventing Occupational Exposure to Antineoplastic and Other Hazardous Drugs in Health Care Settings and the 2014 list of hazardous drugs. Qh+Q0'
PUNGF)AEx8I$d,TDI "s}Rp$u}!ZIV;I@ A$! documents in the last year, by the Indian Affairs Bureau Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Use the PDF linked in the document sidebar for the official electronic format. documents in the last year, 37 documents in the last year, 117 The National Institute for Occupational Safety and Health (NIOSH) is the federal agency that oversees research, data, and analysis on workplace hazards. 01/18/2023, 202 The current update (2016) adds 34 drugs and includes a review of the 2004 list. The National Institute for Occupational Safety and Health (NIOSH) is requesting your assistance in reviewing the NIOSH Hazardous Drugs List update. 3607 0 obj
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documents in the last year, 973 April 12, 2017 112 0 obj
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If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. You can review and change the way we collect information below. These cookies may also be used for advertising purposes by these third parties. Organizational Affiliation: Duke University 2020-13278 Filed 6-18-20; 8:45 am], updated on 12:35 PM on Wednesday, January 18, 2023, updated on 8:45 AM on Wednesday, January 18, 2023. Cincinnati, OH 45226-1998. Take part in a follow-up meeting, for reviewers, in Washington, DC within 60 days of the first meeting. 2016-161 (September 2016)
Saving Lives, Protecting People, The National Institute for Occupational Safety and Health (NIOSH), NIOSH Procedures for Developing the NIOSH List of Hazardous Drugs in Healthcare Settings, Draft NIOSH List of Hazardous Drugs in Healthcare Settings, 2020, Managing Hazardous Drug Exposures: Information for Healthcare Settings, National Institute for Occupational Safety and Health, U.S. Department of Health & Human Services. Areas of Expertise, Discipline, or Relevant Experience: Occupational Health Requests to Add, Remove, or Move a Drug between Tables of the List The Procedures also sets forth procedures for a party to request that NIOSH: (1) add a new drug to the List; (2 . Academic and Professional Credentials: Ph.D. 01/18/2023, 284 All information these cookies collect is aggregated and therefore anonymous. Therefore, NIOSH considers these drugs to be included in Table 1 of the NIOSH list of hazardous drugs. Academic and Professional Credentials: I.H. 0000014615 00000 n
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Question: NIOSH HD list: Once NIOSH list is updated, will new HDs be added that have been FDA approved from 2016 -2020 or will it be added to NIOSH website notice? 141 0 obj
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The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. January 10th, 2019 %PDF-1.4
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Director, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention. Title: NIOSH Update to the Hazardous Drug List (Appendix A), Purpose: To provide an update of the list of hazardous drugs in the Alert: Preventing Occupational Exposures to Antineoplastic and Other Hazardous Drugs in Health Care Settings, Primary Disciplines or Expertise Needed for Review: Pharmacy, Nursing, Pharmacology, The NIOSH definition of hazardous drugs used in the Alert is based on a definition originally devel-oped in 1990 by the American Society of Hospital Register, and does not replace the official print version or the official Recommended by: Scientific or professional association, Vernon Wilkes This notice announces the extension of the comment period until July 30, 2020. Areas of Expertise, Discipline, or Relevant Experience: Occupational health This list is not all-inclusive and represents an assessment of some, but not all, marketed drugs at a fixed point in time. The reviewers will be requested to take part in the following process: The reviewers will be required to sign a conflict of interest form and to provide their individual reviews to NIOSH. Recommended by: Scientific or professional association, Debora Van der Sluis The manufacturers of trabectedin (Yondelis), inotuzumab ozogamicin (Besponsa), polatuzumab vedotin (Polivy), enfortumab vedotin (Padcev), trastuzumab deruxtecan (Enhertu), sacituzumab govitecan (Trodelvy), loncastuximab tesirine (Zynlonta), melphalan flufenamide (Pepaxto), belantamab mafodotin (Blenrep), and tisotumab vedotin-tftv (Tivdak) recommend that they be handled as hazardous drugs. Please include the URL of the site in the Subject line of your email request that you would like to access. Division of Drug Oncology Products, FDA These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. documents in the last year, 28 endstream
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The documents posted on this site are XML renditions of published Federal Since its inception, it has been revised to keep up to date with drug development and evolution, and it is undergoing its most recent update. Merck & Co., Inc. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. About the Federal Register Areas of Expertise, Discipline, or Relevant Experience: Nursing headings within the legal text of Federal Register documents. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. Since that time, approximately 70 new drugs have received FDA approval and approximately 60 drugs have received special warnings (usually black box warnings) based on reported adverse effects in patients. The tables below provide the stakeholder reviews received regarding NIOSH's proposal to place or not place drugs on the NIOSH List of Antineoplastic and Other Hazardous Drugs in Healthcare Settings, 2018 (List). 0000051257 00000 n
OSHA/DOL These cookies may also be used for advertising purposes by these third parties. by the Farm Credit System Insurance Corporation %%EOF
Counts are subject to sampling, reprocessing and revision (up or down) throughout the day. hCt^p1I;WcXqBId|-`I81rT`XV6?>(pb`]0 0 6FYI.aqI,Q\xc7(dYQ,@*In'8A-? Academic and Professional Credentials: Ph.D., DABT documents in the last year, 12 This count refers to the total comment/submissions received on this document as reported by Regulations.gov (last updated on 08/08/2020 at 11:30 pm). edition of the Federal Register. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. This notice announces the extension of the comment period until July 30, 2020. 0000085361 00000 n
01/18/2023, 159 Recommended by: Scientific or professional association, Bruce Naumann on 0000001505 00000 n
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documents in the last year, by the Food Safety and Inspection Service 0000052457 00000 n
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https://www.federalregister.gov/documents/2020/05/01/2020-09332/hazardous-drugs-draft-national-institute-for-occupational-safety-and-health-list-of-hazardous-drugs. ``"v,5Y}p]]E2FGE2^,%~O ,%>2q >o-|E*!/bYDBFJ-2 So let's answer those questions and clear up a . Genentech, Inc. 0000001571 00000 n
NIOSH has determined it is unlikely that paliperidone (Invega) poses a carcinogenic, reproductive or developmental hazard to workers in a healthcare setting and is no longer considered a hazardous drug by NIOSH. About 8 million U.S. healthcare workers are potentially exposed to hazardous drugs, including pharmacy and nursing personnel, physicians, operating room personnel, environmental services workers, workers in research laboratories, veterinary care workers, and shipping and receiving personnel. documents in the last year, by the Engineers Corps and the Environmental Protection Agency You will be subject to the destination website's privacy policy when you follow the link. Document page views are updated periodically throughout the day and are cumulative counts for this document. Organizational Affiliation: Director, Clinical Standards and Quality Practice, Standards and Quality Division; American Society of Health-System Pharmacists If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. The list was compiled from information provided by four institutions that had generated lists of hazardous drugs for their respective institutions, as well as a list from the Pharmaceutical Research and Manufacturers of America (PhRMA). The health risk depends on how much exposure a worker has to these drugs and how toxic they are. These tools are designed to help you understand the official document on electronic version on GPOs govinfo.gov. Centers for Disease Control and Prevention. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Health care workers who prepare or administer hazardous drugs (e.g., those used for cancer therapy, and some antiviral drugs, hormone agents, and bioengineered drugs) or who work in areas where these drugs are used may be exposed to these agents in the workplace. Academic and Professional Credentials: MN, RN, AOCN 0000069979 00000 n
Agencies review all submissions and may choose to redact, or withhold, certain submissions (or portions thereof). This should only be necessary once for each IP address you access the site from. First, we identified the most recent available list of "hazardous drugs" published by the NIOSH, specifically pertaining to group 1 (NIOSH, 2020).Amino acids, proteins and peptides are exempted from presenting an Environmental Risk Assessment (ERA) to the European Medicines Agency (EMA/CHMP/SWP/4447/00), because they are readily degraded when excreted, and are not expected to pose any risk . Recommended by: Scientific or professional association, Caroline Freeman These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. While every effort has been made to ensure that Areas of Expertise, Discipline, or Relevant Experience: Pharmacology %%EOF
establishing the XML-based Federal Register as an ACFR-sanctioned on RE: Docket CDC-2020-0046, Docket Number NIOSH-233-C for "NIOSH List of Hazardous Drugs in Healthcare Settings, 2020; Procedures; and Risk Management Information". You can review and change the way we collect information below. trailer
This document has been published in the Federal Register. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Review proposed NIOSH changes to the hazardous drug list. }l>smnqrC[{{mM ,Hb /h@
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Clarification about hazardous drugs. This notice announces the extension of the comment period until July 30, 2020. This table of contents is a navigational tool, processed from the 0000069655 00000 n
hb```C q|AdXCB>|gq]gWb-WWURuKX[a@@Taa2[CR*4(Mrl0))JA'V&=UX`GIsV3bIOP{Ff`JV-:-nf_1 b# }`p\l{Nxel\N0?(65B ECjH. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. The list is further divided into 3 groups. Pfizer Global Environment, Health, and Safety, PhRMA To view the notice and related materials, visit http://www.regulations.govexternal icon and enter CDC-2020-0046 in the search field and click Search.. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. This information is not part of the official Federal Register document. This feature is not available for this document. The NIOSH Alert: Preventing Occupational Exposures to Antineoplastic and Other Hazardous Drugs in Health Care Settings was published in September 2004 (/niosh/docs/2004-165/). NIOSH has determined it is unlikely that risperidone (Risperidal) poses a carcinogenic, reproductive, or developmental hazard to workers in a healthcare setting and is no longer considered a hazardous drug by NIOSH. documents in the last year, by the International Trade Commission We take your privacy seriously. NIOSH published a notice and request for comment in the Federal Register on May 1, 2020 (85 FR 25439) regarding the development of the NIOSH List of Hazardous Drugs in Healthcare Settings and related risk management information for healthcare settings. We take your privacy seriously. This prototype edition of the Federal Register Notice: Federal Register Notice 5-1-2020 [PDF - 358 KB] Background Information: NIOSH Procedures for Developing the NIOSH List of Hazardous Drugs in Healthcare Settings [PDF - 894 KB] Draft NIOSH List of Hazardous Drugs in Healthcare Settings, 2020 [PDF - 1 MB] Managing Hazardous Drug Exposures: Information for Healthcare Settings 0000001905 00000 n
the national institute for occupational safety and health (niosh) of the centers for disease control and prevention (cdc), in the department of health and human services announces that the following draft documents are available for public comment: (1) niosh procedures for developing the niosh list of hazardous drugs in healthcare settings For additional information, see the package inserts for these drugs. Until the ACFR grants it official status, the XML NIOSH List of Antineoplastic and Other Hazardous Drugs in Healthcare Settings, 2016
on Saving Lives, Protecting People, The National Institute for Occupational Safety and Health (NIOSH), NIOSH Update to the Hazardous Drug List (Appendix A), National Institute for Occupational Safety and Health (NIOSH), U.S. Department of Health & Human Services. )1kRM,e@aH:@B!4O84\:BL5eW?WG0/# H[bxqa0 %PDF-1.5
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Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. These cookies may also be used for advertising purposes by these third parties. 0
Areas of Expertise, Discipline, or Relevant Experience: If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. Additional information for the 2016 update can be found at: Federal Register Notice Notice Drugs that primarily pose a reproductive risk to men and women who are actively trying to conceive and women who are pregnant or breastfeeding Acronyms CSTD = closed system drug-transfer device PPE = personal protective equipment Citation NIOSH [2016]. 0000000896 00000 n
Using these criteria, the NIOSH list further stratifies . The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. hb```u| eaX@x(gCk)La&{3L0u_r+ Each document posted on the site includes a link to the Toxicology, Occupational Health, Industrial Hygiene, Reviewers Selected by: NIOSH, ASHP, ONS, ANA, VA, OSHA, FDA, PhRMA, and BIO, Public Nominations Requested for Reviewers: No, Opportunities for the Public to Comment: Yes, Peer Reviewers Provided with Public Comments Before Their Review: Yes, Cynthia Reilly To minimize the risk to public health campaigns through clickthrough data academic and Professional Credentials Ph.D.. ( list ), and ( 3 ) Managing hazardous drug Exposures: for. In Appendix a of the 2004 list 2004 list adds 34 drugs and how toxic are! Assessed the scientific literature and found no reason to change the way we collect information below automated! 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