My doctor told me to test then and acted as if that wasnt too early. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. Fortunately got low risk for chromosomal anomalies Just the baby's sex was inconclusive! I waited 13 days for my Harmony test results and the nurse finally called me back today to tell me my test was inconclusive! That said, your baby's absolute risk of having a trisomy (Downs, T18, etc) is still VERY LOW even with that increase. Ive done nipt through generations and Harmony both reputable brands and they would never give results with that low of a fraction, as it could come from contamination from say, the person drawing the bloods or the one analysing touching the tube to read results. Unlike most DNA, which is found inside a cell's . If noninvasive prenatal testing indicates that the fetus is at risk for a chromosomal disorder, your provider may recommend diagnostic testing. Create an account or log in to participate. They tell your provider how likely it is that a condition exists. Healthcare providers may recommend it if you: The American College of Obstetricians and Gynecologists (ACOG) used only to recommend NIPT for pregnant people considered high risk. H Hawaiimomma22 Nov 30, 2017 at 12:44 AM @veneziana, Fetal fraction can be defined as the amount of fetal DNA present in the mother's blood. First test, done at 12 weeks, took 2 weeks for them to get back to me and say was inconclusive, so I had a redraw a week and a half ago at 14 weeks. Thats a good sign that your embryo is normal! All rights reserved. I did my NIPT bloodwork at 9w 4d and am supposed to have my results back this Friday. I have read this is an issue for plus size women and . I've had he NIPT test twice now and had it come back for low fetal DNA. I just did a retest last week because mine came back inconclusive!! Diagnostic testing may be recommended after you get NIPT test results. Please specify a reason for deleting this reply from the community. I'm panicking now because I'm so worried. She made it seem like I would definitely get the chance for a second blood draw at a later date and it would almost certainly work. endstream endobj 73 0 obj <>stream I was 164 pre pregnancy and 184 now. We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. Hope you are getting all the support you need and sending good healthy babe energy your way! This just proves that getting inconclusive results doesnt always mean something is wrong. think twice before sharing personal details, foster a friendly and supportive environment, remove fake accounts, spam and misinformation, delete posts that violate our community guidelines, reviewed by our medical review board and team of experts. So I just found out that my NIPT came back with low fetal fraction for the second time. The doctor said I had a perfect ultrasound. I dont understand why it didnt work for me. I have my anatomy scan on Wednesday but Im just so terrified they will give me bad news. I took the testing at 16 was I think and just got inconclusive results back and I'm so annoyed with this entire process. inconclusive results due to low fetal fraction. Both said due to low fetal DNA at 2.6% and 2.7% respectively. I have read this is an issue for plus size women and the other factor is age. My doc told me 2 inconclusive tests raises the risk level significantly in my age. Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. What youre referring to is the NP test. Good luck to you! Anyone else go through this and get good results? Mumsnet carries some affiliate marketing links, so if you buy something through our posts, we may get a small share of the sale (more details here). This limbo state is the worst. Has anyone had this happen to them or know someone? This pregnancy has been so stressful so far 0 A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. Your healthcare provider can answer any questions you have, but ultimately you have to decide how a genetic or chromosomal disorder affects you and your family based on your situation. praying for you and your son or daughter to receive good results! Inconclusive NIPT results twice : hello, just wondering if this has happened to anyone? 15/01/2022 20:53. Ultimately, we learned we were having a baby girl who did not test positive for trisomy but have still been advised to do an amniocentesis procedure at 16 weeks for ultimate peace of mind. Inconclusive NIPT twice! Prenatal tests like NIPT are optional, and getting the test is entirely up to you. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. I had to do the NIPT test twice. NIPT test done twice.with inconclusive results twice. Wish we did like other pregnancies and skipped the testing! They could well be inaccurate- most companies require at least 3%. We strive to provide you with a high quality community experience. Check with your insurance provider before testing to be sure. What was the outcome? My anatomy scan is the 16th so praying everything will come back normal. Results from NIPT tests can sometimes take up to two weeks, although results are often available sooner. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. My baby is in under 5th percentile and doc says it looks like there are severe growth restrictions and an abnormally big head/small body ratio so I think that once we have the CVS answer we will have to man up and make decisions as I hate to think that that it may be in pain etc. K/!0p8v?vbs#.TOc %>.n>pJKps,m0T7-r*Y:p HB&~=^D_|+wIG0s(i]A[p{{9lfvrXiOsd$f{U&K>VY?-3K?gHG|;%nG\O#@'u}mtlDFCgoo>oH![mM*rYauM('@6Gsyc1ER91`o8vk@02>n]FFPl?#=p""?qoir7.[ RU'^G'ulAI$EW0]_.6L8Le. We had issues with our genetic testing as well and I too was super worried! No, its not necessary. How far along were you when you took each one? SMFM 2015: A failed result on noninvasive prenatal testing (NIPT) may provide insight into what subsequent tests may find, research reveals. So bizarre this happens. It's not like my weight was a surprise to them. Australian post natal pack provided to all new parents. Maybe call the clinic directly for feedback on how that particular radiologist writes reports. Which is less than it would normally be for my age. For example, you may get a positive or high-risk result for trisomy 13 but a negative or low-risk result for Down syndrome. I had to wait about 10 days for bouth times I did NIPT, only to get inconclusive results. yes, I have the 12 week scan scheduled for tomorrow evening + bloods then - maybe it will be a different lab this time and it will work. I wish you well mama! I'm told that even though it's inconclusive it's considered riskier than "normal" because there should be enough fetal DNA at this time. Cleveland Clinics Ob/Gyn & Womens Health Institute is committed to providing world-class care for women of all ages. The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. My doctor told me to test then and acted as if that wasnt too early. (https://www.nichd.nih.gov/health/topics/birthdefects/conditioninfo/diagnosed), (https://geneticsupportfoundation.org/pregnancy-101/). Would I do something different knowing the fetus has a genetic condition or an increased risk for a genetic condition? Well, my redraw came back inconclusive, but the NT ultrasounds were reassuring (I am carrying twins). Really sending you love and support. The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. Noninvasive prenatal testing (NIPT) has become popular with many physicians in screening pregnant patients. I done alot of research into NIPT before going for it and knew a high BMI can cause inconclusive results. This is my second baby and I didnt do NIPT with my first. Find advice, support and good company (and some stuff just for fun). NIPT testing is optional. I am so confused and stressed. It has to be at least above 4 percent to give a conclusive result. No markers or bright spots. Has anyone had this? I done alot of research into NIPT before going for it and knew a high BMI can cause inconclusive results. My anatomy scan went well and the doctor has no other concerns at this point. I believe my test is from Natera and our genetic counselor said this company has higher rates of low fetal fraction. I had a redraw last week and waiting for that to come back. I also did NIPT twice and bouth times it came back inconclusive due to low fetal fraction. . I'm 36 weeks now. Myriad is able to magnify the fetal fraction found in your blood.. My first test was at 10 weeks (FF=4.8%) and my second was at 14 weeks-she didn't tell me over the phone what it was. HW[o[~G~ mHc}pHV"=. Certain prenatal screening tests like NIPT are very accurate for conditions such as Down syndrome, but less so for rare genetic conditions. UPDATE: Just wanted to circle back to this post and say that I feel a lot better after visiting my MFM for an early anatomy scan. Get useful, helpful and relevant health + wellness information. endstream endobj 70 0 obj <>/Metadata 17 0 R/PageLayout/OneColumn/Pages 67 0 R/StructTreeRoot 23 0 R/Type/Catalog/ViewerPreferences<>>> endobj 71 0 obj <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageC]/XObject<>>>/Rotate 0/StructParents 0/Tabs/S/Type/Page>> endobj 72 0 obj <>stream I had an inconclusive harmony test at 10 weeks exactly, I wasn't too worried as it was really early, I was on blood thinners, and a higher bmi of 30, all of which can lead to an inconclusive result. My nipt/panorama/harmony results came back inconclusive both times. Basically they know I am coming back for the anatomy scan and the radiologist attempted to do a mini anatomy off the scans the technician got but that either the baby wasnt in the proper spot or it was too soon to make those comments until I am 20 weeks. This educational content is not medical or diagnostic advice. 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